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Food Sci Biotechnol. 2018 Jan 17;27(3):859-866. doi: 10.1007/s10068-018-0312-6. eCollection 2018 Jun.

Improvement of a GC-MS analytical method for the simultaneous detection of 3-MCPD and 1,3-DCP in food.

Author information

1
New Hazardous Substances Team, Department of Food Safety Evaluation, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, 187, Osongsaengmyeong 2-ro, Osong-eup, Heungdeok-gu, Cheongju-si, Chungcheongbuk-do 28159 South Korea.

Abstract

Chloropropanols such as 3-monochloropropane-1,2-diol (3-MCPD) and 1,3-dichloropropan-2-ol (1,3-DCP) are produced by heat treatment in the presence of fat and hydrochloric acid during the manufacture of food stuffs such as hydrolyzed vegetable protein and soy sauce. 3-MCPD and 1,3-DCP have been detected in several foods. An efficient, highly selective GC-MS method was developed to determine the concentration of 3-MCPD and 1,3-DCP in food. Calibration curves for 3-MCPD and 1,3-DCP were constructed, and a correlation of determination (r2) ≥ 0.9990 was obtained. The limits of detection and quantitation for 3-MCPD in food were 0.6 and 2.0 µg/kg, respectively, and those for 1,3-DCP were 0.2 and 0.6 µg/kg, respectively. To the best of our knowledge, this GC-MS-based method is a newly improved analytical procedure for the simultaneous separation and determination of 3-MCPD and 1,3-DCP, at once and at low levels (µg/kg).

KEYWORDS:

1,3-Dichloropropan-2-ol; 3-Monochloropropane-1,2-diol; Chloropropanol; Gas chromatography–mass spectrometry; Hydrolyzed vegetable protein (HVP)

Conflict of interest statement

Compliance with ethical standardsAll authors declare no conflict of interest.

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