Development of Health Products from Natural Sources

Curr Med Chem. 2019;26(24):4606-4630. doi: 10.2174/0929867325666180926152139.

Abstract

BioActive Compounds (BACs) recovered from food or food by-product matrices are useful in maintaining well being, enhancing human health, and modulating immune function to prevent or to treat chronic diseases. They are also generally seen by final consumers as safe, non-toxic and environment-friendly. Despite the complex process of production, chemical characterization, and assessment of health effects, BACs must also be manufactured in stable and bioactive ingredients to be used in pharmaceutical, food and nutraceutical industry. Generally, vegetable derivatives occur as sticky raw materials with pervasive smell and displeasing flavor. Also, they show critical water solubility and dramatic stability behavior over time, involving practical difficulties for industrial use. Therefore, the development of novel functional health products from natural sources requires the design of a suitable formulation to delivery BACs at the site of action, preserve stability during processing and storage, slow down the degradation processes, mask lousy tasting or smell, and increase the bioavailability, while maintaining the BACs functionality. The present review focuses on human health benefits, BACs composition, and innovative technologies or formulation approaches of natural ingredients from some selected foods and by-products from industrial food transformations.

Keywords: C. aurantium peel; Citrus bergamia juice; Health products; annurca peels; hazelnut by-products; soy..

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents, Phytogenic / chemistry
  • Antineoplastic Agents, Phytogenic / therapeutic use
  • Biological Products / chemistry*
  • Biological Products / therapeutic use
  • Citrus / chemistry
  • Citrus / metabolism
  • Corylus / chemistry
  • Corylus / metabolism
  • Glycine max / chemistry
  • Glycine max / metabolism
  • Humans
  • Isoflavones / chemistry
  • Isoflavones / therapeutic use
  • Metabolic Diseases / drug therapy
  • Neoplasms / drug therapy
  • Neoplasms / pathology
  • Polyphenols / chemistry
  • Polyphenols / therapeutic use

Substances

  • Antineoplastic Agents, Phytogenic
  • Biological Products
  • Isoflavones
  • Polyphenols