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Ann Indian Acad Neurol. 2018 Jul-Sep;21(3):173-178. doi: 10.4103/aian.AIAN_491_17.

Clinical Mimickers of Amyotrophic Lateral Sclerosis-Conditions We Cannot Afford to Miss.

Author information

1
Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.
2
Department of Neurology, Neurosciences Centre, All India Institute of Medical Sciences, New Delhi, India.

Abstract

Giving a diagnosis of amyotrophic lateral sclerosis to a patient is akin to handing out a death certificate. However, not all patients presenting with the classical dysphagia, wasting, and weakness may have motor neuron diseases. In these cases, it is extremely important not to miss little cues which can suggest an alternative diagnosis and in many cases a lease of life in terms of a treatment option. In this review, we consider some clinical scenarios that can present with the same symptom complex as diseases involving motor neurons but have a different anatomical or etiopathological basis and in many cases even a therapeutic option.

KEYWORDS:

Amyotrophic lateral sclerosis; lower motor neuron; mimickers; upper motor neuron

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