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Hormones (Athens). 2019 Mar;18(1):65-70. doi: 10.1007/s42000-018-0069-6. Epub 2018 Sep 25.

Asymptomatic and normocalcemic hyperparathyroidism, the silent attack: a combo-endocrinology overview.

Author information

1
Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
2
Department of Endocrinology & Diabetes, 251 Hellenic Air Force & VA General Hospital, Athens, Greece.
3
First Department of Pharmacology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
4
Department of Endocrinology & Metabolism, 424 General Military Hospital, Ring Road, 564 29, N. Efkarpia, Thessaloniki, Greece. a.anastasilakis@gmail.com.

Abstract

Asymptomatic primary hyperparathyroidism (PHPT) and the new variant of PHPT, normocalcemic PHPT, are considered by many physicians as mild, innocuous forms of disease, requiring nothing more than monitoring. Although this may be true in some cases in which the disease does not progress or cause complications, deterioration with more or less severe manifestations may occur. In the present review, we discuss the existing evidence of both the classic (skeletal and renal) and non-classic (cardiovascular, gastrointestinal, and psychiatric) features that have been attributed to asymptomatic and normocalcemic PHPT and the treatment effect on them.

KEYWORDS:

Asymptomatic; Bone; Hyperparathyroidism; Normocalcemic; Renal

PMID:
30255479
DOI:
10.1007/s42000-018-0069-6
[Indexed for MEDLINE]

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