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Cureus. 2018 Jul 22;10(7):e3026. doi: 10.7759/cureus.3026.

Primary Splenic Diffuse Large B-Cell Lymphoma: A Rare Case of Massive Splenomegaly and Thrombocytopenia.

Author information

1
Internal Medicine/Residency, Fairview Hospital/Cleveland Clinic, Cleveland, USA.
2
School of Arts and Sciences, Case Western Reserve University, Cleveland, USA.
3
Hematology and Oncology, Fairview Hospital/Cleveland Clinic, Cleveland, USA.
4
Department of Hematology and Oncology, Fairview Hospital/Cleveland Clinic, Cleveland, USA.

Abstract

Primary splenic diffuse large B-cell lymphoma (DLBCL) is a rare type of non-Hodgkin's lymphoma. It often presents with abdominal pain or splenomegaly. We present a case of a 68-year-old male who presented to the emergency department with left sided abdominal pain. Workup revealed massive splenomegaly and thrombocytopenia. A splenic biopsy confirmed the diagnosis of primary splenic DLBCL. The patient was treated with chemotherapy. This case highlights the importance of considering primary splenic DLBCL with splenomegaly and treating it with chemotherapy and/or splenectomy.

KEYWORDS:

hcv; primary splenic dlbcl; r-chop; splenectomy; splenomegaly; thrombocytopenia

Conflict of interest statement

The authors have declared that no competing interests exist.

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