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Ayu. 2017 Jul-Dec;38(3-4):133-138. doi: 10.4103/ayu.AYU_201_17.

Clinical efficacy of Baladi Manduram in the management of Amlapitta.

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Department of Rasa Shastra and Bhaishajya Kalpana, S. V. Ayurvedic College, Tirupati, Andhra Pradesh, India.
Department of Roga Nidana, S. V. Ayurvedic College, Tirupati, Andhra Pradesh, India.



Amlapitta is a commonly encountered disease of Annavaha Srotasa (gastrointestinal system) described in various classical Ayurvedic texts. The cardinal features of Amlapitta are Avipaka (indigestion), HritkanthaDaha (heart and throat burn) and Tikta-Amlodgara (sour and bitter belching). This disease can be correlated with gastroesophageal reflux disease based on the clinical features. BaladiManduram is one of the unique formulations mentioned in RasaKamadhenu indicated for the management of Amlapitta.


This study is aimed to evaluate the efficacy of BaladiManduram in the management of Amlapitta.

Materials and Methods:

A non-randomized, single-armed, open-labeled clinical trial was conducted in thirty patients having classical symptoms of Amlapitta, administered with 500 mg of BaladiManduram twice a day after meals for 30 days. The assessment was done based on subjective parameters, i.e., Amlodgara (sour belching), Daha (heart burn), Gaurava (heaviness), Utklesha (nausea), Avipaka (indigestion) and KshudhaAlpata (loss of appetite). The results were statistically analyzed using the paired t-test.


Statistically highly significant relief (P < 0.001) was noted in Amlodgara, HritkanthaDaha, Utklesha and Agnimandya and statistically highly significant relief (P < 0.01) was seen in Gaurava and Avipaka.


BaladiManduram can be considered as an effective formulation in the management of Amlapitta.


Amlapitta; Baladi Manduram; gastroesophageal reflux disease

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