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Am J Transplant. 2019 Apr;19(4):1098-1108. doi: 10.1111/ajt.15124. Epub 2018 Oct 16.

Multiple listing in lung transplant candidates: A cohort study.

Author information

1
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Stanford University, Stanford, California.
2
Quantitative Sciences Unit, Department of Medicine, Stanford University, Stanford, California.

Abstract

Lung transplant candidates can be waitlisted at more than one transplant center, a practice known as multiple listing. The factors associated with multiple listing and whether multiple listing modifies waitlist mortality or likelihood of lung transplant is unknown. US lung transplant waitlist candidates were identified as either single or multiple listed using data from the Scientific Registry of Transplant Recipients. Characteristics of single and multiple listed candidates were compared and multivariable logistic regression was used to estimate associations with multiple listing. Multiple listed candidates were matched to single listed candidates using a combination of exact and propensity score matching methods. Cox proportional hazard models were used to estimate the relationship of multiple listing on waitlist mortality and receiving a transplant. Multiple listing occurred in 2.3% of lung transplant waitlist candidates. Younger age, female gender, white race, short stature, high antibody sensitization, college or postcollege education, lower lung allocation score, and a cystic fibrosis diagnosis were independently associated with multiple listing. Multiple listing was associated with an increased likelihood of lung transplant (adjusted hazard ratio [aHR] 2.74, 95% CI 2.37 to 3.16) but was not associated with waitlist mortality (aHR 0.99, 95% CI 0.68 to 1.44).

KEYWORDS:

clinical research/practice; disparities; ethics and public policy; lung disease; lung transplantation/pulmonology; organ allocation; organ procurement and allocation; registry/registry analysis; waitlist management

PMID:
30253057
PMCID:
PMC6433482
[Available on 2020-04-01]
DOI:
10.1111/ajt.15124

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