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Eye Contact Lens. 2019 Jan;45(1):19-22. doi: 10.1097/ICL.0000000000000535.

Efficacy of Plate Expression of Meibum on Tear Function and Ocular Surface Findings in Meibomian Gland Disease.

Author information

1
Department of Ophthalmology (N.A., M.S., J.S.), Tokyo Dental College, Ichikawa General Hospital, Ichikawa, Japan; Department of Ophthalmology (N.A., M.S., M.K., K.T.), Keio University School of Medicine, Tokyo, Japan; and Takasago Eye Clinic (S.O.), Takasago, Japan.

Abstract

PURPOSE:

To evaluate the clinical effectiveness of expression treatment on meibomian gland disease (MGD).

METHODS:

Seventeen right eyes of 17 patients with MGD were divided into 3 groups in this randomized prospective clinical study: no expression group: routine treatment with no expression (five patients, five eyes); digital expression group: routine treatment with digital expression (five patients, five eyes); and plate expression group: routine treatment with plate expression (seven patients, seven eyes). All groups received the same routine treatment for 1 month. Tear film break-up time (TBUT), vital staining scores, meibum expressibility, and the dry eye-related quality of life score (DEQS) questionnaire results were assessed before and 1 month after treatment.

RESULTS:

There was a statistically significant difference of posttreatment TBUT among groups as determined by one-way analysis of variance (P<0.05). A post hoc test revealed that TBUT was statistically significantly higher in plate expression group compared with digital expression group. The fluorescein staining score did not show a statistically significant difference among the groups. Meibum expressibility and the DEQS scores improved in all groups.

CONCLUSION:

Plate expression when used as an adjunct to routine medical management of MGD has been found to be a comparatively effective treatment in terms of improvement of tear film stability compared with no expression or digital expression.

PMID:
30252688
DOI:
10.1097/ICL.0000000000000535
[Indexed for MEDLINE]

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