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J Clin Pharmacol. 2018 Oct;58 Suppl 10:S123-S139. doi: 10.1002/jcph.1140.

Vaccine Update: Recent Progress With Novel Vaccines, and New Approaches to Safety Monitoring and Vaccine Shortage.

Author information

1
St. Luke Medical Centre, Kilimani Area, Kisumu, Kenya.
2
Faculty of Tropical Medicine, Mahidol University, Thailand.
3
Hanover University of Applied Sciences and Arts, Hanover, Germany.
4
University Children's Hospital Zurich, Zurich, Switzerland.
5
Flor M. Munoz, MD, Baylor College of Medicine, Houston, TX, USA.
6
Global Healthcare Consulting, New Delhi, India.
7
Erasmus University Medical Center, Rotterdam, The Netherlands.
8
Department of Global Health, University of Washington, Seattle, WA, USA.
9
Department of Infection and Immunity, Monash Children's Hospital, Monash Health, Victoria, Australia.
10
SAEFVIC, Murdoch Childrens Research Institute, Victoria, Australia.
11
School of Population Health and Preventive Medicine, Monash University, Melbourne, Australia.
12
University of Basel Children's Hospital, Basel, Switzerland.
13
Brighton Collaboration Foundation, Basel, Switzerland.

Abstract

Vaccines are increasingly based on new constructs, new technologies, and new compounds. Novel immunization programs are rapidly implemented globally. In this article, we highlight selected hot topics of this highly dynamic and broad field of scientific and public health development. The first section focuses on novel vaccines including malaria, dengue, serogroup B meningococcal, and respiratory syncytial virus vaccines and antibodies. The second section is addressing emerging strategies and programmatic challenges including maternal immunization, integrated mother-child safety monitoring, and finally coping strategies with vaccine shortages.

KEYWORDS:

antibodies; dengue; malaria; maternal immunization; meningitis; prevention; respiratory syncytial vaccine; safety; vaccine shortage; virus

PMID:
30248195
DOI:
10.1002/jcph.1140
[Indexed for MEDLINE]

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