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Clin Rehabil. 2019 Feb;33(2):233-240. doi: 10.1177/0269215518801440. Epub 2018 Sep 24.

Addition of blood flow restriction to passive mobilization reduces the rate of muscle wasting in elderly patients in the intensive care unit: a within-patient randomized trial.

Author information

1
1 Faculdade de Educação Física e Dança, Universidade Federal de Goiás, Goiânia, Brasil.
2
2 Centro de Ciências Biológicas e da Saúde, Universidade da Amazônia, Belém, Brasil.
3
3 Centro de Ciências da Saúde, Universidade Católica de Pelotas, Pelotas, Brasil.
4
4 Centro de Ciências Biológicas e da Saúde, Centro Universitário do Estado do Pará, Belém, Brasil.
5
5 Escola Superior de Educação Física, Universidade Federal de Pelotas, Pelotas, Brasil.
6
6 Faculdade de Educação Física, Universidade Federal do Pará, Castanhal, Brasil.

Abstract

OBJECTIVE::

To evaluate the addition of blood flow restriction to passive mobilization in patients in the intensive care unit.

DESIGN::

The study was a within-patient randomized trial.

SETTING::

Two intensive care units in Belém, from September to October 2017.

SUBJECTS::

In total, 34 coma patients admitted to the intensive care unit sector, and 20 patients fulfilled the study requirements.

INTERVENTIONS::

All participants received the passive mobilization protocol for lower limbs, and blood flow restriction was added only for one side in a concurrent fashion. Intervention lasted the entire patient's hospitalization time.

MAIN OUTCOME MEASUREMENT::

Thigh muscle thickness and circumference.

RESULTS::

In total, 34 subjects were enrolled in the study: 11 were excluded for exclusion criteria, 3 for death, and 20 completed the intervention (17 men and 3 women; mean age: 66 ± 4.3 years). Despite both groups presented atrophy, the atrophy rate was lower in blood flow restriction limb in relation to the control limb (-2.1 vs. -2.8 mm, respectively, in muscle thickness; P = 0.001). In addition, the blood flow restriction limb also had a smaller reduction in the thigh circumference than the control limb (-2.5 vs. -3.6 cm, respectively; P = 0.001).

CONCLUSION::

The use of blood flow restriction did not present adverse effects and seems to be a valid strategy to reduce the magnitude of the rate of muscle wasting that occurs in intensive care unit patients.

KEYWORDS:

Muscle atrophy; blood flow restriction; intensive care unit; passive manipulation

PMID:
30246555
DOI:
10.1177/0269215518801440
[Indexed for MEDLINE]

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