[CO2 LASER for the treatment of vaginal symptoms of genitourinary syndrome of menopause]

Gynecol Obstet Fertil Senol. 2018 Nov;46(10-11):729-734. doi: 10.1016/j.gofs.2018.09.001. Epub 2018 Sep 18.
[Article in French]

Abstract

Genitourinary syndrome of menopause (GSM) brings together a collection of signs including vaginal dryness, burning sensation and itching discomfort as well as deterioration of sexual health, dysuria, urgenturia and repeated urinary infections and may be responsible for a significant impairment of quality of life in symptomatic postmenopausal women. The management of GSM therefore represents a public health issue. Systemic or local hormonal treatments are frequently offered, as well as non-hormonal treatments. The existence of contraindications to hormonal treatments and the constraints of using local treatments lead us to propose other therapeutic options. CO2 LASER is now part of the therapeutic arsenal for the treatment of vaginal dryness in the context of GSM. There is a growing interest in this technique, especially for women who have a contraindication to hormonal therapy, as it is a globally effective, long-acting alternative with very little adverse effect. Current evidence suggests that this tool could provide a quality of life benefit to many patients with minimal side effect exposure, if used in the respect of its indications and implementation protocols. However, clinical data based on high-level therapeutic trials remain absolutely essential for this treatment to be validated and recommended by health professionals.

Keywords: Atrophie vulvo-vaginale; Estrogènes locaux; Fractional CO(2) laser therapy; Genitourinary syndrome of menopause; Hormonothérapie systémique; Laser fractionné au CO(2); Local estrogens; Syndrome génito-urinaire de la ménopause; Systemic hormonotherapy; Vulvo-vaginal atrophy.

MeSH terms

  • Dysuria
  • Female
  • Female Urogenital Diseases / surgery*
  • Humans
  • Lasers, Gas / adverse effects
  • Lasers, Gas / therapeutic use*
  • Menopause*
  • Quality of Life
  • Reproducibility of Results
  • Sexual Health
  • Syndrome
  • Vaginal Diseases / surgery*