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Fortschr Neurol Psychiatr. 2018 Sep;86(S 01):S34-S42. doi: 10.1055/a-0681-6700. Epub 2018 Sep 21.

[Nutritional aspects in Parkinson's disease: disease risk, dietary therapy and treatment of digestive tract dysfunction].

[Article in German; Abstract available in German from the publisher]

Author information

1
Gertrudis Klinik Biskirchen, Karl-Ferdinand-Broll Straße 2-4, 35638 Leun-Biskirchen.
2
Klinik und Poliklinik für Neurologie, Universitätsmedizin Mainz, Langenbeckstr. 1, 55131  Mainz.
3
Neurologisches Zentrum, Segeberger Kliniken, Hamdorfer Weg 3, 23795 Bad Segeberg und Department Performance, Neuroscience, Therapy and Health, Medical School Hamburg, Am Kaiserkai 1, 20457 Hamburg.
4
Klinik für Neurologie, St. Joseph-Krankenhaus Berlin-Weißensee, Gartenstraße 1, 13088 Berlin.
5
Klinik für Neurologie, Klinikum Lippe, Rintelner Straße 85, 32657 Lemgo.
6
Department für Neurologie, Universitätsklinikum Münster, Albert-Schweitzer Campus 1, Gebäude A1, 48149  Münster.
7
Klinik und Poliklinik für Neurologie, Universitätsklinikum Bonn und Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE e. V., Bonn).

Abstract

in English, German

Epidemiological studies suggest an association of certain foods with the risk of Parkinson's disease. Also, a number of studies revaeled positive effects on disease progression by caffeine, higher uric acid and total cholesterol levels - especially in men. However, it is not yet clear whether a specific dietary concept or the effects of the intestinal microbiota on the human metabolism could play a role in the course of the disease. Given the lack of prospective nutrition studies, only general recommendations can be given: a "balanced" seasonal regional diet with emphasis on vegetables, fruits, nuts, fish, low amount of red meat, and non-processed foods with a low level of simple carbohydrates may be helpful. Especially for the elderly, a low-protein diet should be avoided. Rather, in order to prevent the development of sarcopenia and malnutrition, particular attention must be paid to adequate protein intake. The supply of vitamins B12 and D3 must be ensured - at the same time, the non-critical use of dietary supplements, especially micronutrients with presumed anti-oxidative properties, should be discouraged.

PMID:
30241099
DOI:
10.1055/a-0681-6700

Conflict of interest statement

Die Autoren geben an, dass kein Interessenkonflikt besteht.

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