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Pediatr Infect Dis J. 2018 Sep 19. doi: 10.1097/INF.0000000000002199. [Epub ahead of print]

Diarrhea-Associated Mortality in Children Less Than 5 Years of Age in the United States, 2005-2016.

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National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA.


Diarrheal disease morbidity decreased after the 2006 US introduction of rotavirus vaccine. We calculated diarrheal death rates for children who were <5 years of age during 2005-2016. Death rates declined from 2.3/100,000 (2005-2006) to 1.7/100,000 (2014-2016). Declines were seen among 1-23 month olds, white and black children. Further exploration of the role of rotavirus vaccine in decreasing deaths among children is warranted.

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