Format

Send to

Choose Destination
Gynecol Obstet Invest. 2018 Sep 20:1-8. doi: 10.1159/000493264. [Epub ahead of print]

Use of the Endometriosis Fertility Index to Predict Natural Pregnancy after Endometriosis Surgery: A Single-Center Study.

Kim JS1, Lee CW1, Yun J2, Lee JH2, Yun BH3,2, Park JH1,3, Seo SK3,2, Cho S1,3, Choi YS3,2, Lee BS3,2.

Author information

1
Department of Obstetrics and Gynecology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
2
Department of Obstetrics and Gynecology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
3
Institute of Women's Life Medical Science, Yonsei University College of Medicine, Seoul, Republic of Korea.

Abstract

AIMS:

Our objective was to predict natural pregnancy after endometriosis surgery using the endometriosis fertility index (EFI).

METHODS:

A retrospective medical records review was conducted, examining patients surgically treated for endometriosis at a single center in Korea between January 2009 and February 2015. In total, 68 women attempting natural conception were analyzed by assessing age, preoperative serum CA-125, body mass index, revised American Fertility Society (rAFS) stage, EFI, and pregnancy outcome. Kaplan-Meier estimates and log-rank tests were used to generate cumulative natural pregnancy rate curves based on an EFI cut-point. A receiver-operating characteristic (ROC) curve was plotted for EFI.

RESULTS:

Seventy-seven patients attempted conceptions, resulting in 33 natural and 9 assisted conceptions. Excluding assisted conceptions, the mean EFI scores of 68 women who were not pregnant and pregnant were 5.43 ± 0.36 and 6.88 ± 0.28 respectively. The relation between EFI and natural pregnancy was significant (cumulative overall pregnancy rate, p = 0.006), whereas rAFS stage was not (univariate logistics, p = 0.853). The cut-point for maximum natural pregnancy outcomes was 6 (area under ROC curve = 0.710, 95% CI 0.586-0.835).

CONCLUSION:

The EFI is a reliable staging system for predicting natural pregnancy after endometriosis surgery. EFI scores can be used to guide postoperative treatment of women with endometriosis.

KEYWORDS:

Cumulative pregnancy rate; Endometriosis; Endometriosis fertility index; Fertility

PMID:
30235446
DOI:
10.1159/000493264

Supplemental Content

Full text links

Icon for S. Karger AG, Basel, Switzerland
Loading ...
Support Center