Format

Send to

Choose Destination
Adv Exp Med Biol. 2018;1086:141-156. doi: 10.1007/978-981-13-1117-8_9.

Microbiota and Aging.

Author information

1
MOE Key Laboratory of Protein Sciences, School of Pharmaceutical Sciences, Tsinghua University, Beijing, China.
2
School of Pharmaceutical Sciences, Tsinghua University, Beijing, China. zwang@tsinghua.edu.cn.

Abstract

The human gut microbiota is a huge ecosystem that provides lots of functions for host development, immune system, and metabolism. Gut microbiota is linked to lots of diseases, including human metabolic diseases such as obesity, type 2 diabetes (T2D), irritable bowel syndrome, and cardiovascular disease (CVD). Few studies, however, have noted the relationship between aging and microbiota; the connection between aging and microbiota remains largely to be researched. In this review, recent research findings are summarized on the role of gut microbiota in aging processes with emphasis on therapeutic potential of microbiome-targeted interventions in antiaging medicine.

KEYWORDS:

Aging; Aging-related diseases; Fecal transplantation; Gut microbiota

PMID:
30232757
DOI:
10.1007/978-981-13-1117-8_9
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center