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Wien Med Wochenschr. 2018 Sep 18. doi: 10.1007/s10354-018-0651-1. [Epub ahead of print]

[Reduction the risk in pediatric anesthesia-what should we know-what should we do].

[Article in German]

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Univ. Klinik f. Anästhesie, perioperative Medizin und allgemeine Intensivmedizin, Salzburger Landeskliniken, Paracelsus Medizinische Privatuniversität, Strubergasse 22, 5020, Salzburg, Österreich.
Abteilung für Anästhesie und Intensivmedizin, Klinik Hallerwiese/Cnopf'sche Kinderklinik, Nürnberg, Deutschland.
Anästhesieabteilung, Universitäts-Kinderspital Zürich, Zürich, Schweiz.
Extraordinarius für Kinderanästhesie, Universität Zürich, Zürich, Schweiz.


Pediatric anesthesia has always been conjuncted with higher risk than anesthesia for adults (JP Morray; Pediatric Anesthesia 2011;21:722-9). Not only the imminent critical events, but also, caused by recently published data, the theoretical neurotoxicity of anesthetic agents and a potencial negative influence of anesthetics on braindevelopement, are in the spotlight.Concerns about the neurodevelopement and the general warnings from the U.S. Food and Drug Administration (FDA) for anesthesia in young children led to a worldwide discussion about safety in pediatric anesthesia (FDA Safety Anouncement 2017).Beside these theoretical risks, which are based only on animal research, we have to pay much more attention to the widely spread out poor quality of anesthesia in children.The following article should summarize the state of science about the risks and the opportunities to minimize them.


Neurotoxicity; Pediatric anesthesia; Safety


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