Format

Send to

Choose Destination
Int J Clin Pharmacol Ther. 2018 Dec;56(12):612-616. doi: 10.5414/CP203266.

Predictability of serum vancomycin concentrations using the kinetic estimated glomerular filtration rate formula for critically ill patients
.

Abstract

OBJECTIVE:

To evaluate the predictability of serum vancomycin concentrations of critically ill patients using the new kinetic estimated glomerular filtration rate (KeGFR) and other three established eGFR formulae.

MATERIALS AND METHODS:

We calculated serum vancomycin concentrations using software provided by the manufacturer of vancomycin.

RESULTS:

Data were collected from 122 hospitalized adults. The mean error and mean absolute error of KeGFR were 0.81 µg/mL and 4.46 µg/mL, respectively. The root mean squared prediction error of KeGFR was the highest (6.67 µg/mL) among the four formulae.

CONCLUSION:

The predictability of KeGFR formula did not show good accuracy in critically ill patients.
.

PMID:
30220291
DOI:
10.5414/CP203266
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Dustri-Verlag Dr. Karl Feistle GmbH & Co. KG
Loading ...
Support Center