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Surg Oncol. 2018 Sep;27(3):490-494. doi: 10.1016/j.suronc.2018.05.029. Epub 2018 May 29.

Predictors of chewing and swallowing disorders after surgery for locally advanced oral cancer with free flap reconstruction: A prospective, observational study.

Author information

1
Department of Otorhinolaryngology, Head and Neck Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan. Electronic address: akira.ohkoshi.e6@tohoku.ac.jp.
2
Department of Otorhinolaryngology, Head and Neck Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-cho, Aoba-ku, Sendai 980-8575, Japan.

Abstract

OBJECTIVE:

Surgery for locally advanced oral cancer often requires wide resections of multiple subsites of the oral cavity, including the oral tongue, floor of the mouth, and lower gingiva, and it causes chewing and swallowing disorders. The aim of this prospective, observational study was to determine which subsites have a greater impact on chewing and swallowing disorders after surgery.

METHODS:

A prospective, observational study was conducted involving 52 patients who underwent surgery for locally advanced oral cancer with free flap reconstruction. The patients' Functional Oral Intake Scale scores were measured before surgery and 1 and 3 months after surgery. Possible predictors of chewing and swallowing disorders were subjected to univariate analysis and multivariate logistic regression analysis. Age, sex, preoperative body mass index, clinical stage, extent of mandibular bone resection, floor of the mouth resection, total or subtotal glossectomy, laryngeal suspension, bilateral neck dissection, and postoperative radiation therapy were the variables evaluated.

RESULTS:

Multivariate logistic regression analysis showed that both anterior or extensive mandibular bone resection and postoperative radiation therapy were independently associated with poor oral intake after surgery.

CONCLUSIONS:

The identified predictors will be helpful for better management of patients identified as being at high risk of chewing and swallowing disorders.

KEYWORDS:

Chewing and swallowing disorder; Functional oral intake scale; Oral cancer

PMID:
30217307
DOI:
10.1016/j.suronc.2018.05.029
[Indexed for MEDLINE]

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