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J Smooth Muscle Res. 2018;54(0):83-90. doi: 10.1540/jsmr.54.83.

MECHANOMEDICINE: applications of mechanobiology to medical sciences and next-generation medical technologies.

Author information

1
Department of Cardiovascular Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan.

Abstract

Mechanical stress underlies most aspects of cell and organismal biology. Mechanomedicine is a field of biology that seeks to understand molecular, cellular, tissue, organ, and individual responses to mechanical stimuli and aims to apply the gained knowledge to improve health. Combining biology and engineering, we explore research areas including mechanosensitive ion channels, heart failure, and regenerative medicine.This review will describe our findings in mechanobiology, our establishment of a joint venture business as we developed devices responding to medical needs, and our alliance with other companies.

KEYWORDS:

bioventure; hemostat; mechanobiology; stretch-activated ion channel

PMID:
30210090
PMCID:
PMC6135919
DOI:
10.1540/jsmr.54.83
[Indexed for MEDLINE]
Free PMC Article

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