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Cureus. 2018 Jul 1;10(7):e2904. doi: 10.7759/cureus.2904.

Early Accreta and Uterine Rupture in the Second Trimester.

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Internal Medicine, Texas Tech University Health Sciences Center of the Permian Basin, Odessa, USA.
MS3/Ross University School of Medicine, California Hospital Medical Center, Los Angeles, USA.
MS4/Ross University School of Medicine, California Hospital Medical Center, Los Angeles, USA.


The differential diagnosis of third trimester bleeding can range from placenta abruptia to placenta previa to uterine rupture and the placenta accreta spectrum (PAS). However, patients with risk factors such as multiple cesarean sections (c-sections), advanced maternal age (AMA), grand multiparity, and single-layer uterine closure are at greater risk of developing these complications earlier than we would traditionally expect. This case recounts a 38-year-old gravida 6 preterm 3 term 1 abortus 1 live 4 (G6P3114) at 23 weeks and five days gestational age (GA) with a past medical history of preterm pregnancy, pre-eclampsia, chronic abruptia, three previous c-sections, and low-lying placenta who presented to the emergency department (ED) with vaginal bleeding. Initial workup revealed placenta accreta and possible percreta. The patient was placed on intramuscular (IM) corticosteroids in anticipation of preterm delivery. As soon as the patient was stable, she was discharged home. She presented to a different hospital the next day with the same complaints. Imaging was consistent with accreta and her presentation with abruption. During the hospital stay, the patient went into threatened preterm labor (PTL). At first, we suspected preterm premature rupture of membranes (PPROM) due to apparent pooling of amniotic fluid in the vaginal canal. Upon further work up, the diagnosis was consistent with chronic abruption oligohydramnios sequence (CAOS). Before this could be investigated, her hospital course was complicated by acute abruption and Category III/nonreassuring fetal heart rate (FHR) tracing. The patient underwent an emergency c-section at 26 weeks GA as well as a planned supracervical hysterectomy for desired permanent sterilization. During the operation, the patient suffered a postpartum hemorrhage (PPH) of 4500 mL. She was later discharged home on postoperative day (POD) eight.


disseminated intravascular coagulation; fetal demise; fetal heart rate tracing; fetal ultrasound; maternal fetal medicine; microangiopathic hemolytic anemia; perinatology; placenta accreta spectrum; uterine rupture; uteroplacental insufficiency

Conflict of interest statement

The authors have declared that no competing interests exist.

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