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J Electrocardiol. 2018 Sep - Oct;51(5):801-808. doi: 10.1016/j.jelectrocard.2018.05.018. Epub 2018 May 30.

Initial validation of a novel ECGI system for localization of premature ventricular contractions and ventricular tachycardia in structurally normal and abnormal hearts.

Author information

1
Division of Cardiology, The Johns Hopkins University School of Medicine, 1800 Orleans St, Zayed 7125, Baltimore, MD 21287, United States. Electronic address: smisra5@jhmi.edu.
2
Cardiac Arrhythmia Center, University of California - Los Angeles, 100 UCLA Medical Plaza, Suite 660, Los Angeles, CA 90095, United States.
3
Division of Cardiology, The Johns Hopkins University School of Medicine, 1800 Orleans St, Zayed 7125, Baltimore, MD 21287, United States.

Abstract

BACKGROUND:

View into Ventricular Onset (VIVO) is a novel ECGI system that uses 3D body surface imaging, myocardial CT/MRI, and 12‑lead ECG to localize earliest ventricular activation through analysis of simulated and clinical vector cardiograms.

OBJECTIVE:

To evaluate the accuracy of VIVO for the localization of ventricular arrhythmias (VA).

METHODS:

In twenty patients presenting for catheter ablation of VT [8] or PVC [12], VIVO was used to predict the site earliest activation using 12‑lead ECG of the VA. Results were compared to invasive electroanatomic mapping (EAM).

RESULTS:

A total of 22 PVC/VT morphologies were analyzed using VIVO. VIVO accurately predicted the location of the VA in 11/13 PVC cases and 8/9 VT cases. VIVO correctly predicted right vs left ventricular foci in 20/22 cases.

CONCLUSION:

View into Ventricular Onset (VIVO) can accurately predict earliest activation of VA, which could aid in catheter ablation, and should be studied further.

KEYWORDS:

Electrocardiographic imaging; Non-invasive mapping; Premature ventricular contractions; Vectorcardiography; Ventricular tachycardia

[Indexed for MEDLINE]

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