Format

Send to

Choose Destination
J Crit Care. 2018 Dec;48:118-123. doi: 10.1016/j.jcrc.2018.08.022. Epub 2018 Aug 21.

qSOFA as predictor of mortality and prolonged ICU admission in Emergency Department patients with suspected infection.

Author information

1
Department of Intensive Care, Austin Hospital, Heidelberg, Melbourne, Victoria, Australia; Data Analytics Research and Evaluation (DARE) Center, Melbourne University and Austin Hospital, Melbourne, Australia.
2
Emergency Department, Austin Health, Heidelberg, Melbourne, Victoria, Australia; School of Medicine, The University of Melbourne, Parkville, Melbourne, Victoria, Australia.
3
Olivia Newton John Cancer Wellness and Research Centre, Austin Health, Department of Radiation Oncology, Melbourne, Victoria, Australia; Sir Peter MacCallum Department of Oncology, Melbourne University, Victoria, Australia.
4
MKM Health, South Yarra, Melbourne, Victoria, Australia.
5
Department of Intensive Care, Austin Hospital, Heidelberg, Melbourne, Victoria, Australia; Data Analytics Research and Evaluation (DARE) Center, Melbourne University and Austin Hospital, Melbourne, Australia; School of Medicine, The University of Melbourne, Parkville, Melbourne, Victoria, Australia; Australian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia. Electronic address: Rinaldo.BELLOMO@austin.org.au.

Abstract

PURPOSE:

We assessed the quick Sequential Organ Failure Assessment (qSOFA) score as a predictor of in-hospital mortality or prolonged ICU stay in Emergency Department (ED) patients with suspected infection.

PATIENTS AND METHODS:

We measured qSOFA in a cohort of 11,205 ED patients with suspected infection. The primary outcome was in-hospital mortality and/or ICU stay ≥3 days.

RESULTS:

The qSOFA score was positive in 2429 (21.7%) patients. In-hospital mortality, and in-hospital mortality or ICU stay ≥3 days were 12.8% and 17.2% respectively for qSOFA positive patients vs 2.2% and 4.2% for qSOFA negative patients (p < .0001). For the prediction of in-hospital mortality, a positive qSOFA had a positive predictive value (PPV) of 13% (95% CI, 11-14) and a negative predictive value (NPV) of 98% (95% CI, 97-98). For the prediction of in-hospital mortality or ICU stay ≥3 days, the PPV and NPV of a positive qSOFA were 17% (95% CI, 16-19) and 96 (95% CI, 95-96), respectively.

CONCLUSION:

Among ED patients with suspected infection, a positive qSOFA identified those at much greater risk of mortality and longer ICU stay.

KEYWORDS:

Emergency department; Infection; Intensive Care Unit; Mortality; Sepsis; qSOFA

PMID:
30176527
DOI:
10.1016/j.jcrc.2018.08.022

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center