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J Coll Physicians Surg Pak. 2018 Sep;28(9):S162-S163. doi: 10.29271/jcpsp.2018.09.S162.

MRI Appearances of Colitis Cystica Profunda: A Rare Benign Mimicker of Colorectal Malignancy.

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Department of Radiology, Shifa International Hospital, Islamabad.


Colitis cystica profunda (CCP) is a rare benign disease characterised by mucin-filled cysts beneath the muscularis mucosae, which commonly involves the rectum and sigmoid colon. The disease process involving rectum is termed as proctitis cystica profunda. Trans-rectal ultrasound (TRUS) and magnetic resonance imaging (MRI) are an aid to diagnosis. However, histological analysis of deep biopsy is diagnostic. We report a case of 21-year male who presented with bleeding per rectum and was diagnosed as solitary ulcer of the rectum (SRUS) on superficial biopsies on sigmoidoscopy. Surgical intervention coupled with MRI findings and histopathological analysis formulated diagnosis of CCP. To our knowledge, we are second to report this entity with its MRI features.

[Indexed for MEDLINE]

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