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Thorac Cancer. 2018 Nov;9(11):1509-1512. doi: 10.1111/1759-7714.12841. Epub 2018 Aug 31.

Invasive thymoma with multiple ring calcifications and osseous metaplasia: A case report.

Jung JJ1,2, Kim SH1,2, Kang DH1,2, Kim KN1,2, Moon SH1,2, Yang JH1,2, Byun JH1,2, Kim JW1,2, Jeon KN3, Bae K3, Kim HC4, Kim JY4, Park HO1,5, Choi JY1,5.

Author information

1
Department of Thoracic and Cardiovascular Surgery, Institute of Health Sciences, Gyeongsang National University School of Medicine, Jinju, South Korea.
2
Department of Thoracic and Cardiovascular Surgery, Gyeongsang National University Changwon Hospital, Changwon, South Korea.
3
Department of Diagnostic Radiology, College of Medicine, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Changwon, South Korea.
4
Division of Pulmonology and Allergy, Department of Internal Medicine, College of Medicine and Institute of Health Sciences, Gyeongsang National University Changwon Hospital, Changwon, South Korea.
5
Department of Thoracic and Cardiovascular Surgery, Gyeongsang National University Hospital, Jinju, South Korea.

Abstract

An 8.0 × 7.0 × 3.0 cm calcified anterior mediastinal mass was found in a 57-year-old man during a regular health checkup. The tumor had invaded the pericardium and phrenic nerve. The Masaoka-Koga classification was stage III. Multiple ring calcifications were present in the gross feature, and osseous metaplasia was observed in the histologic examination. World Health Organization histologic classification of the tumor was type B2. The patient is currently undergoing chemotherapy and radiation therapy to prevent tumor recurrence. To our knowledge, this is the first case of multiple ring calcifications and osseous metaplasia in invasive thymoma.

KEYWORDS:

Multiple ring calcifications; osseous metaplasia; thymoma

PMID:
30168289
PMCID:
PMC6209803
DOI:
10.1111/1759-7714.12841
[Indexed for MEDLINE]
Free PMC Article

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