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Ann Clin Lab Sci. 2018 Jul;48(4):511-516.

Performance and Suitability of Mindray BS480©: A Fully Open Clinical Chemistry Analyzer.

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Department of Biochemistry, Centre de Ressources Biologiques, Lapeyronie Hospital, Montpellier, France.
Department of Biochemistry, Centre de Ressources Biologiques, Lapeyronie Hospital, Montpellier, France



Mindray BS480©, a multi-parametric and random-access clinical chemistry instrument, is suitable for medium-sized hospital applications. Large laboratories in hospital environments require high throughput non-emergency settings that could slow routine production lines. In addition, the possibility to adapt to different methodologies is of great convenience for improving the transfer from manual to automated applications. The aim of the study is to evaluate analytical performances and to draw a comparison between analyzers for most common clinical parameters under simulated routine conditions.


Analytical performances in term of imprecision and comparison studies were performed between Mindray BS480© and reference analyzers such as Cobas 8000© for 12 routine parameters and ABX Pentra 400© for pyruvate and acetoacetate. Mindray BS480© usability, in terms of throughput and emergency sample handling, was also evaluated.


Imprecision CVs for different analytes ranged from 0.7% to 7.9%, and the comparison study regression slope ranged from 0.74 to 1.22. Mindray workflow and emergency modes covered automated specifications.


Results are considered significant for colorimetric, turbidimetric and ISE assays. Most performances were in line with Mindray and current recommendations. Mindray BS480© provides precise measurements for a variety of analytes. The possibility to adapt some methodologies is very useful, leading to a switch from manual methodology to automation.

[Indexed for MEDLINE]

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