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Biochem Biophys Res Commun. 1986 May 14;136(3):1078-82.

The occurrence of cyclic AMP in archaebacteria.

Abstract

Cyclic AMP was found in species representative of the three major groups of the archaebacteria. In Methanobacterium thermoautotrophicum starvation for H2 led to a significant increase in cellular cAMP. The findings suggest that the occurrence of cAMP antedates the divergence of the major kingdoms of biology; the observations also imply that cAMP constitutes a very early regulatory molecule.

PMID:
3013165
DOI:
10.1016/0006-291x(86)90443-2
[Indexed for MEDLINE]

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