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BMC Res Notes. 2018 Aug 20;11(1):604. doi: 10.1186/s13104-018-3707-9.

Spectrum of opportunistic infections and associated factors among people living with HIV/AIDS in the era of highly active anti-retroviral treatment in Dawro Zone hospital: a retrospective study.

Author information

1
Department of Medical Laboratory, Wolaita Sodo University, Wolaita Sodo, Ethiopia. fitha2007@yahoo.com.
2
Department of Midwifery, College of Health Science and Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia.
3
Department of Pharmacy, College of Health Sciences and Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia.
4
Department of Human Nutrition and Reproductive Health, School of Public Health, Wolaita Sodo University, Wolaita Sodo, Ethiopia.
5
School of Medicine, Wolaita Sodo University, Wolaita Sodo, Ethiopia.

Abstract

OBJECTIVES:

The study aims to elucidate the spectrum, magnitude and determining factors of the major opportunistic infections in PLHIV patients currently receiving HAART.

RESULTS:

A retrospective cross-sectional study was conducted at Tercha Hospital from 744 patient cards. The overall all prevalence of opportunistic infection was 658 (88.4%) developed OIs. Pulmonary tuberculosis, 118 (18%), severe community acquired pneumonia 107 (16.3%) and oral candidiasis 103 (15.6%) were the most common opportunistic infections. Disease stage [AOR = 3.22:95% CI 1.76-5.66], CD4 level [AOR = 2.53:95% CI 1.19-5.37], drug adherence [AOR = 3.02:95% CI 1.57-5.77] and hemoglobin [AOR = 2.49:95% CI 1.34-4.62] showed significant association with OIs. Higher magnitude of opportunistic infection with considerable proportion of AIDS defining illness was detected. So empowerment of skilled man power, health education and provision of antimicrobials is mandatory.

KEYWORDS:

Associated factors; Magnitude; OI; PLHIV; Spectrum

PMID:
30126450
PMCID:
PMC6102885
DOI:
10.1186/s13104-018-3707-9
[Indexed for MEDLINE]
Free PMC Article

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