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Nature. 1986 May 15-21;321(6067):219-26.

Correlations between T-cell specificity and the structure of the antigen receptor.

Abstract

The derived amino-acid sequences of the heterodimeric antigen receptors expressed by a series of murine T-cell clones are presented. A comparison of the receptor sequences indicates that several mechanisms for generating receptor diversity can influence T-cell specificity, including junctional diversity, combinatorial joining, and combinatorial chain associations.

PMID:
3012351
DOI:
10.1038/321219a0
[Indexed for MEDLINE]

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