Format

Send to

Choose Destination
J Ren Nutr. 2018 Aug 16. pii: S1051-2276(18)30154-7. doi: 10.1053/j.jrn.2018.06.006. [Epub ahead of print]

Adequacy of Plant-Based Proteins in Chronic Kidney Disease.

Author information

1
Perelman School of Medicine at the University of Pennsylvania, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: afternoonrounds@gmail.com.
2
Perelman School of Medicine at the University of Pennsylvania, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
3
Division of Nephrology and Hypertension, University of California, Irvine, School of Medicine, Orange, California.

Abstract

Concerns regarding protein and amino acid deficiencies with plant-based proteins have precluded their use in chronic kidney disease (CKD) patients. Many of these concerns were debunked years ago, but recommendations persist regarding the use of "high-biological value" (animal-based) proteins in CKD patients, which may contribute to worsening of other parameters such as blood pressure, metabolic acidosis, and hyperphosphatemia. Plant-based proteins are sufficient in meeting both quantity and quality requirements. Those eating primarily plant-based diets have been observed to consume approximately 1.0 g/kg/day of protein, or more. CKD patients have been seen to consume 0.7-0.9 g/kg/day of mostly plant-based protein without any negative effects. Furthermore, those substituting animal-based proteins for plant-based proteins have shown reductions in severity of hypertension, hyperphosphatemia, and metabolic acidosis. Plant-based proteins, when consumed in a varied diet, are not only nutritionally adequate but have pleiotropic effects which may favor their use in CKD patients.

PMID:
30122652
DOI:
10.1053/j.jrn.2018.06.006

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center