Format

Send to

Choose Destination
Am J Prev Med. 2018 Sep;55(3):395-402. doi: 10.1016/j.amepre.2018.04.042.

Replacing Sedentary Time: Meta-analysis of Objective-Assessment Studies.

Author information

1
Department of Physical Education and Sports, University of Seville, Seville, Spain.
2
Laboratorio de Ciencias de la Actividad Física, el Deporte y la Salud, Facultad de Ciencias Médicas, Universidad de Santiago de Chile, Santiago de Chile, Chile.
3
Department of Physical Education and Sports, University of Seville, Seville, Spain; Area of Human Motricity and Sport Performance, University of Seville, Seville, Spain.
4
Department of Physical Education and Sports, University of Seville, Seville, Spain; Department of Physical Activity and Sport, Cardenal Espinola CEU, Seville, Spain.
5
Swinburne University of Technology, Melbourne, Australia; The Baker Heart and Diabetes Institute, Melbourne, Australia.
6
Institute for Applied Health Research, School of Health and Life Science, Glasgow Caledonian University, Glasgow, Scotland, United Kingdom; Department of Sports and Movement Sciences, Ghent University, Ghent, Belgium.
7
Institute for Positive Psychology and Education, Faculty of Health Sciences, Australian Catholic University, Sydney, Australia; Department of Exercise Sciences, University of Auckland, Auckland, New Zealand. Electronic address: borja.delpozocruz@acu.edu.au.

Abstract

CONTEXT:

The aim was to summarize estimates of the potential benefits for cardiometabolic risk markers and all-cause mortality of replacing time spent in sedentary behaviors with light-intensity physical activity or with moderate to vigorous physical activity, from studies using device-based measurement.

EVIDENCE ACQUISITION:

Four databases covering the period up to December 2016 were searched and analyzed (February 2017). Data were extracted by two independent reviewers. For the meta-analyses, the estimated regression coefficients (β) and 95% CIs were analyzed for BMI, waist circumference, and high-density lipoprotein cholesterol. Pooled relative rate and 95% CIs were calculated for fasting glucose, fasting insulin, and homeostatic model assessment-insulin resistance values. Hazard ratios were extracted from studies of all-cause mortality risk.

EVIDENCE SYNTHESIS:

Ten studies (with 17,390 participants) met the inclusion criteria. Reallocation of 30 minutes of sedentary time to light-intensity physical activity was associated with reductions in waist circumference, fasting insulin, and all-cause mortality risk; and with an increase in high-density lipoprotein cholesterol. Reallocating 30 minutes of sedentary time to moderate to vigorous physical activity was associated with reductions in BMI, waist circumference, fasting glucose, fasting insulin, and all-cause mortality (not pooled) and with an increase in high-density lipoprotein cholesterol.

CONCLUSIONS:

Replacing sedentary time with either light-intensity physical activity or moderate to vigorous physical activity may be beneficial, but when sedentary time is replaced with moderate to vigorous physical activity, the predicted impacts are stronger and apparent for a broader range of risk markers. These findings point to potential benefits of replacing sedentary time with light-intensity physical activity, which may benefit those less able to tolerate or accommodate higher-intensity activities, including many older adults.

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center