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J Family Med Prim Care. 2018 May-Jun;7(3):642-644. doi: 10.4103/jfmpc.jfmpc_347_16.

Vitamin B12 deficiency presenting with hyperpigmentation and pancytopenia.

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Family Physician, Akshadha Diabetes and Family Clinic, Vijayawada, Andhra Pradesh, India.


Hyperpigmentation with generalized weakness may be the initial presentation of several systemic conditions. Vitamin B12 deficiency can present very rarely as hyperpigmentation. Association of pancytopenia at this stage is even rare. Early identification and management can prevent various neurological complications. Here, we report a rare case of Vitamin B12 deficiency presenting as hyperpigmentation and pancytopenia.


Hyperpigmentation; Vitamin B12 deficiency; pancytopenia

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