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Nutr Metab Cardiovasc Dis. 2018 Sep;28(9):909-916. doi: 10.1016/j.numecd.2018.05.009. Epub 2018 May 26.

Regular brief interruptions to sitting after a high-energy evening meal attenuate glycemic excursions in overweight/obese adults.

Author information

1
Baker Heart and Diabetes Institute, Melbourne, Australia; Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia. Electronic address: Rachel.Climie@baker.edu.au.
2
Baker Heart and Diabetes Institute, Melbourne, Australia; Department of Physiology, School of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Australia; Health Innovations Research Institute, RMIT University, Melbourne, Australia.
3
Baker Heart and Diabetes Institute, Melbourne, Australia.
4
Baker Heart and Diabetes Institute, Melbourne, Australia; Swinburne University of Technology, Melbourne, Australia.
5
Baker Heart and Diabetes Institute, Melbourne, Australia; Central Clinical School and Department of Physiology, School of Medicine, Nursing & Health Services, Monash University, Melbourne, Australia.
6
School of Public Health, University of Queensland, Brisbane, Australia; Mary MacKillop Institute of Health Research, Australian Catholic University, Melbourne, Australia; School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia; School of Exercise and Nutrition Sciences, Deakin University, Burwood, Australia; School of Sport Science, Exercise and Health, The University of Western Australia, Perth, Australia.

Abstract

BACKGROUND AND AIMS:

Modern Western lifestyles are characterized by consumption of approximately 45% of total daily energy intake at the evening meal, followed by prolonged sitting while watching television (TV), which may deleteriously impact glycemic control. After a high-energy evening meal (dinner), we examined whether regular, brief activity bouts during TV commercial breaks could acutely lower postprandial glucose and insulin responses in overweight/obese adults, compared to prolonged uninterrupted sitting.

METHODS AND RESULTS:

Nine overweight/obese adults (29.7 ± 4.06 kg m-2; aged 32 ± 3 years; 5 male) completed two laboratory-based conditions of three and a half hours: prolonged sitting during TV viewing (SIT); and, prolonged sitting interrupted every 20 min with 3 min of light-intensity body-weight resistance activities (active commercial breaks; ACBs). Venous postprandial glucose and insulin responses to dinner were calculated as positive incremental area under the curve (iAUC) from baseline. Interstitial glucose was measured using a continuous glucose monitor and quantified as total AUC (tAUC). Compared to SIT, plasma glucose iAUC was reduced by 33% [3.4 ± 1.0 vs 5.1 ± 1.0 (mean ± SEM) mmol h·L-1, p = 0.019] and plasma insulin iAUC by 41% (813 ± 224 vs 1373 ± 224, p = 0.033 pmol h·L-1) for the ACB condition. During the ACB condition there was a significant reduction in interstitial glucose tAUC (24.4 ± 5.2 vs 26.9 ± 5.2 mmol h·L-1, p < 0.001), but this did not persist beyond the laboratory observation period.

CONCLUSIONS:

Regular brief light-intensity activity bouts can attenuate glycemic responses during television viewing time following a high-energy evening meal in overweight/obese adults.

KEYWORDS:

Circadian rhythm; Glucose; Obesity; Sedentary

PMID:
30111495
DOI:
10.1016/j.numecd.2018.05.009
[Indexed for MEDLINE]

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