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PLoS Biol. 2018 Aug 13;16(8):e3000003. doi: 10.1371/journal.pbio.3000003. eCollection 2018 Aug.

Why are RNA virus mutation rates so damn high?

Author information

1
School of Environmental and Biological Sciences, Rutgers, the State University of New Jersey, New Brunswick, New Jersey, United States of America.

Abstract

The high mutation rate of RNA viruses is credited with their evolvability and virulence. This Primer, however, discusses recent evidence that this is, in part, a byproduct of selection for faster genomic replication.

PMID:
30102691
PMCID:
PMC6107253
DOI:
10.1371/journal.pbio.3000003
[Indexed for MEDLINE]
Free PMC Article

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