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Vaccine. 2018 Sep 18;36(39):5807-5810. doi: 10.1016/j.vaccine.2018.08.015. Epub 2018 Aug 9.

Colostral transmission of BTV-8 antibodies from dairy cows six years after vaccination.

Author information

1
Department of Livestock Sciences, Research Institute of Organic Agriculture (FiBL), Ackerstrasse 113, Postbox 219, 5070 Frick, Switzerland; Division Veterinary Pharmacology & Toxicology, Department Clinical Research and Veterinary Public Health, Vetsuisse Faculty, University of Bern, Länggassstrasse 124, 3012 Bern, Switzerland. Electronic address: hannah.ayrle@fibl.org.
2
Division Veterinary Pharmacology & Toxicology, Department Clinical Research and Veterinary Public Health, Vetsuisse Faculty, University of Bern, Länggassstrasse 124, 3012 Bern, Switzerland. Electronic address: meike.mevissen@vetsuisse.unibe.ch.
3
Bovine Health Service, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 260, 8057 Zurich, Switzerland. Electronic address: mkaske@vetclinics.uzh.ch.
4
Institute of Virology and Immunology, Sensemattstrasse 293, 3147 Mittelhäusern, Switzerland. Electronic address: andrea.voegtlin@ivi.admin.ch.
5
Institute of Virology and Immunology, Sensemattstrasse 293, 3147 Mittelhäusern, Switzerland. Electronic address: raffael.fricker@ivi.admin.ch.
6
Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Südufer 10, 17493 Greifswald, Insel Riems, Germany. Electronic address: bernd.hoffmann@fli.de.
7
College of Veterinary Medicine, Institute of Immunology, University of Leipzig, Deutscher Platz 5, 04103 Leipzig, Germany. Electronic address: mathias.buettner@uni-leipzig.de.
8
Animalmed GmbH, Mühlerain 385, 5072 Oeschgen, Switzerland. Electronic address: z.marin@sunrise.ch.
9
Department of Livestock Sciences, Research Institute of Organic Agriculture (FiBL), Ackerstrasse 113, Postbox 219, 5070 Frick, Switzerland. Electronic address: michael.walkenhorst@fibl.org.

Abstract

Bluetongue virus (BTV) antibodies were analysed in 27 Swiss calves born in 2016 at the age of 16-19 days using competitive enzyme-linked-immunosorbent-assay (cELISA) and virus neutralization test (VNT) (animal trial permission number: 75684). Obligatory documentation proved that 15 of 27 dams were BTV-8 vaccinated once or three times in 2008-2010. The offsprings of the non-vaccinated dams were seronegative. Two of three calves and 11 of 12 calves descending from dams who had been vaccinated one or three times, respectively, had BTV specific serum antibodies. As Switzerland is considered BTV-free from 2010 to 2016, it is likely that BTV-8 antibodies were transferred via colostrum. Furthermore, we confirmed neutralizing cross-reactivity of BTV-8 with BTV-4 antibodies as 5 samples positive for BTV-8 were also reactive with BTV-4 antibodies.

KEYWORDS:

Bluetongue virus; Cattle; Maternal antibodies; Vaccination

PMID:
30100070
DOI:
10.1016/j.vaccine.2018.08.015
[Indexed for MEDLINE]

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