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Cell. 2018 Aug 9;174(4):785-790. doi: 10.1016/j.cell.2018.07.038.

Microbiome: Focus on Causation and Mechanism.

Author information

1
Department of Bioengineering and ChEM-H, Stanford University and Chan Zuckerberg Biohub, Stanford, CA 94305, USA. Electronic address: fischbach@fischbachgroup.org.

Abstract

There is tremendous enthusiasm for the microbiome in academia and industry. This Perspective argues that in order to realize its potential, the field needs to focus on establishing causation and molecular mechanism with an emphasis on phenotypes that are large in magnitude, easy to measure, and unambiguously driven by the microbiota.

PMID:
30096310
PMCID:
PMC6094951
DOI:
10.1016/j.cell.2018.07.038
[Indexed for MEDLINE]
Free PMC Article

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