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Cell. 2018 Aug 9;174(4):777-779. doi: 10.1016/j.cell.2018.07.024.

Sequencing Diversity One Cell at a Time.

Author information

1
Department of Neurological Surgery, UCSF, San Francisco, CA 94143, USA; Weill Institute for Neurosciences, UCSF, San Francisco, CA 94158, USA. Electronic address: michael.oldham@ucsf.edu.
2
Weill Institute for Neurosciences, UCSF, San Francisco, CA 94158, USA; Gladstone Institutes, San Francisco, CA 94158, USA; Department of Neurology, UCSF, San Francisco, CA 94158 USA; Department of Physiology, UCSF, San Francisco, CA 94158 USA; Kavli Institute for Fundamental Neuroscience, UCSF, San Francisco, CA 94158 USA. Electronic address: anatol.kreitzer@gladstone.ucsf.edu.

Abstract

Single-cell RNA sequencing provides a new approach to an old problem: how to study cellular diversity in complex biological systems. Three studies-Saunders et al., Zeisel et al., and Davie et al.-deploy this technique on an unprecedented scale to reveal transcriptional patterns that distinguish cells in the nervous systems of mice and flies.

PMID:
30096308
DOI:
10.1016/j.cell.2018.07.024
[Indexed for MEDLINE]
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