Format

Send to

Choose Destination
J Stroke Cerebrovasc Dis. 2018 Nov;27(11):3030-3035. doi: 10.1016/j.jstrokecerebrovasdis.2018.06.031. Epub 2018 Aug 6.

Incidence and Predictors of the In-stent Restenosis after Vertebral Artery Ostium Stenting.

Author information

1
Department of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province 210002; Department of Neurology, Xi'an XD group hospital, Xi'an, Shanxi Province 710077, China.
2
Department of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province 210002.
3
Department of Neurology, Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong Province 510260.
4
Department of Neurology, Xi'an XD group hospital, Xi'an, Shanxi Province 710077, China.
5
Department of Neurology, Wuxi People's Hospital of Nanjing Medical University, Wuxi, Jiangsu Province 214023.
6
Department of Intensive Care Unit, The Affiliated Brain Hospital with Nanjing Medical University, Nanjing, Jiangsu Province 210009.
7
Department of Intensive Care Unit, The Third Affiliated Hospitial of Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province 210001, China.
8
Department of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province 210002. Electronic address: zhangrenliang@nju.edu.cn.
9
Department of Neurology, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province 210002. Electronic address: yangfang021011@163.com.

Abstract

BACKGROUND:

The incidence and predictors for in-stent restenosis (ISR) was not fully explored. We aim to investigate the incidence and predictors of ISR after stenting at the origin of vertebral artery.

MATERIALS AND METHODS:

Two hundred and six patients with 229 stents implantation between July 1, 2005 and July 31, 2015 were included in the study. All patients underwent conventional clinical and angiographic (digital subtraction angiography) follow-up at around 6 months post procedure. ISR was defined as greater than 50% stenosis within or immediately (within 5 mm) adjacent to the stent. Multivariate Cox regression analyses were utilized to investigate the predictors for ISR.

RESULTS:

The ISR was found in 30 patients (30/206, 14.6%) with 31 lesions (31/229, 13.5%) with the mean follow-up duration of 11.1-month (range: 3 - 92 months). Stent diameter (hazard ratio 0.504, 95% confidence interval 0.294 - 0.864) was an independent predictor for ISR.

CONCLUSION:

ISR rate after Vertebral artery ostium stent placement is acceptable, which was conversely associated with the stent diameter.

KEYWORDS:

In-stent restenosis—Vertebral artery ostium—Ischemic stroke—Atherosclerotic stenosis

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center