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World J Gastroenterol. 2018 Aug 7;24(29):3204-3221. doi: 10.3748/wjg.v24.i29.3204.

Helicobacter pylori and extragastric diseases: A review.

Author information

1
Dipartimento di "Medicina di Precisione", UOC Epatogastroenterologia, Università della Campania "Luigi Vanvitelli", Napoli 80131, Italy.
2
Dipertimento Di Scienze Mediche e Chirurgiche, Università di Bologna, Bologna 40138, Italy.
3
Dipartimento di "Medicina di Precisione", UOC Epatogastroenterologia, Università della Campania "Luigi Vanvitelli", Napoli 80131, Italy. marco.romano@unicampania.it.

Abstract

Helicobacter pylori (H. pylori) infection is very common and affects approximately half of the world population. It causes gastric diseases, but some authors have reported an association of H. pylori infection with other systemic manifestations beginning in 1994. The list of potential effects of H. pylori outside the stomach includes a number of extragastric manifestations and we focused on neurological, dermatological, hematologic, ocular, cardiovascular, metabolic, allergic, and hepatobiliary diseases. This review discusses these important reported manifestations that are not related to the gastrointestinal tract.

KEYWORDS:

Allergic diseases; Cardiovascular diseases; Dermatological diseases; Extragastric disease; Helicobacter pylori; Hematologic diseases; Hepatobiliary diseases; Metabolic diseases; Neurological diseases; Ocular diseases

PMID:
30090002
PMCID:
PMC6079286
DOI:
10.3748/wjg.v24.i29.3204
[Indexed for MEDLINE]
Free PMC Article

Conflict of interest statement

Conflict-of-interest statement: The authors have no conflicts of interest and no financial support.

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