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Kardiologiia. 2018 Jul;(7):59-65.

[Epicardial Fat and Atrial Fibrillation: the Role of Profibrinogenic Mediators].

[Article in Russian]

Author information

1
Federal State Budgetary Institution, "A.N. Bakulev Science Center of Cardiovascular Surgery" of the RF Ministry of Health Care.

Abstract

BACKGROUND:

Epicardial adipose tissue (EAT) has certain paracrine functions, which could be associated with proinflammatory and fibrotic changes in myocardium even in patients without structural heart disease but with atrial fibrillation (AF).

PURPOSE:

to evaluate interrelationship between clinical data, parameters of tissue Doppler imaging (TDI), EAT thickness estimated by magnetic resonance imaging (MRI), and biochemical markers of fibrosis and inflammation in patients with nonvalvular AF without concomitant ischemic heart disease (IHD).

MATERIALS AND METHODS:

We included in this study 39 AF patients without valvular pathology or IHD with normal or moderately increased left atrial (LA) dimension (mean age 50.8±13.9 years, 49 % men). The following groups were distinguished for analysis: with idiopathic AF (iAFgroup, n=21); with AF and arterial hypertension (AF+AH group, n=18); with normal (.

KEYWORDS:

atrial fibrillation; epicardial fat; magnetic resonance tomography; myocardial fibrosis markers

PMID:
30081810

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