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Pediatr Emerg Care. 2018 Aug;34(8):588-591. doi: 10.1097/PEC.0000000000001576.

Lyme Arthritis: An Update for Clinical Practice.

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Academic Chief of Emergency Department Education, Valley Children's Hospital, Clovis and Clinical Instructor (Affiliate) of Emergency Department, Stanford University School of Medicine, Stanford, CA (Long).
Assistant Professor of Clinical Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.


Lyme disease is the most common vector-borne illness in North America, with the majority of cases occurring in the Northeast and upper Midwest. Lyme arthritis is the most prevalent manifestation of late-stage Lyme disease. Lyme arthritis typically presents as a monoarthritis or oligoarthritis in large joints such as the knee. Accompanying positive 2-tier Lyme serologies or polymerase chain reaction from synovial fluid/tissue is considered diagnostic for patients from an endemic area. The mainstay of initial treatment is a prolonged course of oral antibiotics.

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