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Int J Gynaecol Obstet. 2018 Nov;143(2):205-210. doi: 10.1002/ijgo.12638. Epub 2018 Aug 16.

Effects of prophylactic uterine artery embolization on second-trimester induced abortions in patients with placenta previa.

Author information

1
Department of Gynecology and Family Planning, Women's Hospital School of Medicine Zhejiang University, Hangzhou, China.
2
Department of Gynecology and Obstetrics, Jiubao Street Community Health Service Center, Hangzhou, China.
3
Department of Gynecology and Obstetrics, Central Hospital of Haining, Jiaxing, China.

Abstract

OBJECTIVE:

To evaluate the effects of prophylactic uterine artery embolization (UAE) on second-trimester induced abortions in patients with placenta previa.

METHODS:

The present study was a retrospective review of second-trimester induced abortions in the presence of placenta previa that conducted between January 1, 2008, and October 31, 2017, at a university hospital in Hangzhou, China. Pregnancy outcomes including intraoperative blood loss, transfusion, dilatation and evacuation, hysterotomy delivery, and hysterectomy were compared between patients with and without prophylactic UAE.

RESULTS:

There were 54 patients included in the study. In patients with partial placenta previa (n=15), the volume of intraoperative blood loss and the frequency of dilatation and evacuation were not significantly different between the UAE and non-UAE groups (P>0.05). No patient had a transfusion, hysterotomy delivery, or hysterectomy. Among patients with complete placenta previa (n=39), the volumes of intraoperative blood loss (P=0.014) and transfusion (P=0.046) were significantly lower in the UAE group compared with the non-UAE group. The rates of dilatation and evacuation, and hysterotomy delivery did not differ between the groups (P>0.05), but were numerically higher in the non-UAE group. No patient was treated with hysterectomy.

CONCLUSION:

Prophylactic UAE before a second-trimester induced abortion had significant advantages in women with complete placenta previa, but it did not improve the pregnancy outcome in patients with partial placenta previa.

CHINESE CLINICAL TRIAL REGISTRY:

ChiCTR-OPC-14005334.

KEYWORDS:

Ethacridine lactate; Mifepristone; Placenta previa; Pregnancy outcomes; Second-trimester induced abortion; Uterine artery embolization

PMID:
30076600
DOI:
10.1002/ijgo.12638
[Indexed for MEDLINE]

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