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J Neurotrauma. 2018 Aug 15;35(16):1858-1863. doi: 10.1089/neu.2018.5871.

The Canadian Traumatic Brain Injury Research Consortium: Epitomizing Collaborative Research in Canada.

Author information

1 Department of Critical Care, The Hospital for Sick Children , Toronto, Ontario, Canada .
2 Neuroscience and Mental Health Research Program, The Hospital for Sick Children Research Institute , Toronto, Ontario, Canada .
3 Interdepartmental Division of Critical Care, The University of Toronto , Toronto, Ontario, Canada .
4 Institute of Medical Science, The University of Toronto , Toronto, Ontario, Canada .
5 Sport Injury Prevention Research Centre, Faculty of Kinesiology, University of Calgary , Calgary, Alberta, Canada .
6 Hotchkiss Brain Institute, Alberta Children's Hospital Research Institute, O'Brien Institute for Public Health, Cumming School of Medicine, University of Calgary , Calgary, Alberta, Canada .
7 School of Physical and Occupational Therapy, McGill University , Montréal, Québec, Canada .
8 Trauma Center, Montreal Children's Hospital, McGill University Health Center , Montréal, Québec, Canada .
9 CHU de Québec - Université Laval Research Center , Population Health and Optimal Health Practices Research Unit (Trauma - Emergency - Critical Care Medicine), Québec City, Québec, Canada .
10 Ontario Neurotrauma Foundation , Toronto, Ontario, Canada .
11 Brain Injury Canada , Ottawa, Ontario, Canada .
12 Department of Pathology and Laboratory Medicine, Djavad Mowafaghian Centre for Brain Health, University of British Columbia , Vancouver, British Columbia, Canada .
13 Department of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, Université Laval , Québec City, Québec, Canada .


Traumatic brain injury (TBI) is the leading cause of death in the first half of life and a chronic disability for Canadians of all ages. Despite the recognized importance of TBI, there is no integrated national strategy for research and best practices in Canada. We therefore created the Canadian TBI Research Consortium (CTRC) to build an ideal model of collaboration between Canadian TBI researchers. Our objectives were to: (1) Create a collaborative Canadian research network, (2) improve patient survival, functional outcome, and health through sustainable and scalable evidence-based practice implementation, (3) strengthen the healthcare system for patients with TBI, (4) provide international leadership and collaboration in TBI research, (5) build stronger links with patients and their representatives to help set the research agenda, and to participate in analysis of its impacts, and (6) support current researchers and prepare the next generation of leaders in TBI research. Building on the highly successful 30-year history of the Canadian Critical Care Trials Group, we developed a highly collaborative research group that integrates the multi-disciplinary network of TBI researchers in Canada. The CTRC conducts multi-center clinically relevant practice changing research. Our research is developed around investigator-led project-based research using a programmatic approach and multiple methodologies. Through strong and sustainable career development and mentorship programs, we train and develop the next generation of TBI researchers. Our group is composed of more than 100 Canadian researchers from coast to coast, most of them funded by the Canadian Institutes of Health Research and other granting agencies. In conclusion, the CTRC prioritizes investigator-led TBI research and broadens the research agenda by integrating researchers from different disciplines in the field of TBI research to optimize delivery of care and improve the health of Canadians with TBI. Our goals are being accomplished across the whole continuum of care by conducting clinically relevant and practice-changing research.


collaboration; investigator-led; programmatic approach; research network

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