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Gene. 1985;40(2-3):331-6.

The sequence of foot-and-mouth disease virus RNA to the 5' side of the poly(C) tract.

Abstract

The nucleotide sequence of foot-and-mouth disease virus (FMDV) RNA to the 5' side of the poly(C) tract (S fragment) has been determined for representatives of the A and O serotypes of the virus. The two S fragments differ in length by five nucleotides (nt), with 367 nt for O1 compared with 362 nt for A10, due to a number of insertions/deletions. However, the two sequences show 86% homology. There are no conserved open reading frames (ORFs). Secondary structure predictions reveal a high degree of potential base-pairing, such that the entire S fragment sequence can be folded into a hairpin structure.

PMID:
3007298
DOI:
10.1016/0378-1119(85)90057-5
[Indexed for MEDLINE]

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