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Rev Invest Clin. 2018;70(4):153-157. doi: 10.24875/RIC.18002544.

[Clinical Applications of Next-Generation Sequencing].

Author information

1
Genomics Laboratory, Red de Apoyo a la Investigación, Universidad Nacional Autónoma de México - Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
2
CONACYT-Instituto Nacional de Cancerología, Mexico City, Mexico.

Abstract

The significant drop in sequencing costs boosted by chemistries optimization and sample multiplexation has resulted in an immense growth within the field of next-generation sequencing (NGS) in the last decade. This has allowed a diversification of techniques, promoting a rapid advance in knowledge on the molecular basis of human disease. Due to the applicability and importance of this technology in basic research, it has quickly migrated to the clinical setting. NGS enables clinicians to make improved diagnostic and treatment decisions, which ultimately may influence precision medicine.

KEYWORDS:

Clinical diagnostics; Clinical genomics; Next-generation sequencing

PMID:
30067721
DOI:
10.24875/RIC.18002544
[Indexed for MEDLINE]
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