Diphasic or prolonged course of viral hepatitis A in children

Boll Ist Sieroter Milan. 1985;64(6):443-6.

Abstract

A study on nine cases of diphasic viral hepatitis A was carried out in 130 children admitted to pediatric hospital from January to December 1982. One hundred and eight children (83.0%) showed IgM anti-HAV (one of them was a chronic HBsAg carrier), 19 (14.6%) were HBsAg positive at the admission and 3 (2.3%) became positive for anti-HBc IgM marker during the course of the illness. Nine anti-HAV IgM positive children showed an atypical course of their disease in that after a short period of progressive enzyme level normalization, a relapse occurred without signs of subsequent HBV, CMV or EBV infection. Probable although hypothetical interpretations of these cases are discussed.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Cytomegalovirus / immunology
  • Hepatitis A / immunology
  • Hepatitis A / physiopathology*
  • Hepatitis A Antibodies
  • Hepatitis Antibodies / analysis
  • Hepatitis B Antibodies / analysis
  • Hepatitis B Surface Antigens / analysis
  • Humans
  • Immunoglobulin M / analysis
  • Infant

Substances

  • Hepatitis A Antibodies
  • Hepatitis Antibodies
  • Hepatitis B Antibodies
  • Hepatitis B Surface Antigens
  • Immunoglobulin M