Imaging findings in radiation therapy complications of the central nervous system

Jpn J Radiol. 2018 Sep;36(9):519-527. doi: 10.1007/s11604-018-0759-7. Epub 2018 Jul 24.

Abstract

Radiation therapy is a useful treatment for tumors and vascular malformations of the central nervous system. Radiation therapy is associated with complications, including leukoencephalopathy, radiation necrosis, vasculopathy, and optic neuropathy. Secondary tumors are also often seen long after radiation therapy. Secondary tumors are often benign tumors, such as hemangiomas and meningiomas, but sometimes malignant gliomas and soft tissue sarcomas emerge. We review the imaging findings of complications that may occur after brain radiation therapy.

Keywords: Radiation necrosis; Radiation therapy; Radiation-induced glioma; Radiation-induced sarcoma; Radiation-induced vasculopathy.

Publication types

  • Review

MeSH terms

  • Brain Neoplasms / pathology
  • Brain Neoplasms / radiotherapy*
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Neoplasms, Radiation-Induced / diagnostic imaging*
  • Radiation Injuries / diagnostic imaging*
  • Tomography, X-Ray Computed / methods*