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Rev Esp Med Nucl Imagen Mol. 2018 Sep - Oct;37(5):315-317. doi: 10.1016/j.remn.2018.02.001. Epub 2018 Jul 2.

A rare case of a 123I-MIBG SPECT/CT positive, but 68Ga-DOTA-TOC PET/CT negative pheochromocytoma of the bladder.

[Article in English, Spanish]

Author information

1
Department of Nuclear Medicine, Medical University Innsbruck, Innsbruck, Austria. Electronic address: alexander.kroiss@i-med.ac.at.
2
Department of Nuclear Medicine, Medical University Innsbruck, Innsbruck, Austria.
3
Department of Urology, Medical University Innsbruck, Innsbruck, Austria.
4
Department of Internal Medicine I, Medical University Innsbruck, Innsbruck, Austria.

Abstract

Pheochromocytoma (PHEO) is rare and belongs to the group of neuroendocrine tumours (NETs). These tumours can be found anywhere from the neck to the pelvis associated with sympathetic ganglia. Morphological imaging, for example CT, provides excellent anatomical detail and high sensitivity but lacks specificity as difficulties may occur when distinguishing between tumours derived from the sympathetic nervous system and other tumour entities. In contrast to anatomical imaging, functional imaging (123I-MIBG, 68Ga-DOTA-TOC PET) provides high sensitivity and specificity in detecting NETs. Early detection of PHEO is crucial and has a major effect on treatment and prognosis. This case report describes the important role of anatomical and functional imaging in a patient with a neuroendocrine tumour of unusual origin.

KEYWORDS:

(123)I-MIBG SPECT/CT; (123)I-MIBG SPECT/TC; (68)Ga-DOTA-TOC PET/CT; (68)Ga-DOTA-TOC PET/TC; Feocromocitoma; Pheochromocytoma

PMID:
30042056
DOI:
10.1016/j.remn.2018.02.001

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