Send to

Choose Destination
Phytother Res. 2018 Nov;32(11):2131-2145. doi: 10.1002/ptr.6157. Epub 2018 Jul 24.

Ethnobotany of the genus Taraxacum-Phytochemicals and antimicrobial activity.

Author information

Department of Medical Parasitology, Zabol University of Medical Sciences, Zabol, Iran.
Plant Breeding Institute, Sydney Institute of Agriculture, University of Sydney, Sydney, New South Wales, Australia.
Department of Food Science, Rutgers University, New Brunswick, New Jersey, USA.
Laboratório de Microbiologia e Biologia Molecular - LMBM, Departamento de Química Biológica - DQB, Universidade Regional do Cariri - URCA, Pimenta, Crato, Brazil.
Department of Pharmaceutical Technology, Avicenna Tajik State Medical University, Dushanbe, Tajikistan.
Medical Ethics and Law Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Student Research Committee, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Botany, Lahore College for Women University, Lahore, Pakistan.
Department of Range and Watershed Management, Faculty of Natural Resources, University of Zabol, Zabol, Iran.
Departamento de Ingeniería Química, Ambiental y de los Materiales, Universidad de Jaén, Jaén, Spain.
Department of Biomedical, Surgical and Dental Sciences, Milan State University, Milan, Italy.
Department of Botany and Postgraduate Department, Biological Sciences, VIVA College of Arts, Science and Commerce, Virar, Maharashtra, India.
Department of Agricultural and Environmental Sciences, Milan State University, Milan, Italy.
Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Chemistry, Richardson College for the Environmental Science Complex, The University of Winnipeg, Winnipeg, Manitoba, Canada.


Plants belonging to the genus Taraxacum have been used in traditional healthcare to treat infectious diseases including food-borne infections. This review aims to summarize the available information on Taraxacum spp., focusing on plant cultivation, ethnomedicinal uses, bioactive phytochemicals, and antimicrobial properties. Phytochemicals present in Taraxacum spp. include sesquiterpene lactones, such as taraxacin, mongolicumin B, and taraxinic acid derivatives; triterpenoids, such as taraxasterol, taraxerol, and officinatrione; and phenolic derivatives, such as hydroxycinnamic acids (chlorogenic, chicoric, and caffeoyltartaric acids), coumarins (aesculin and cichoriin), lignans (mongolicumin A), and taraxacosides. Aqueous and organic extracts of different plant parts exhibit promising in vitro antimicrobial activity relevant for controlling fungi and Gram-positive and Gram-negative bacteria. Therefore, this genus represents a potential source of bioactive phytochemicals with broad-spectrum antimicrobial activity. However, so far, preclinical evidence for these activities has not been fully substantiated by clinical studies. Indeed, clinical evidence for the activity of Taraxacum bioactive compounds is still scant, at least for infectious diseases, and there is limited information on oral bioavailability, pharmacological activities, and safety of Taraxacum products in humans, though their traditional uses would suggest that these plants are safe.


Taraxacum; antibiotic resistance; antimicrobial activity; food preservatives; functional foods; nutraceuticals

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center