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Am J Clin Pathol. 2018 Aug 30;150(4):353-363. doi: 10.1093/ajcp/aqy062.

Optimal Intraoperative Assessment of Gastric Margins.

Author information

1
Department of Pathology, Yale University School of Medicine, New Haven, CT.
2
School of Public Health, Yale University, New Haven, CT.

Abstract

Objectives:

Intraoperative pathology consultation (IOC) to assess margins is frequently requested during surgery of the stomach and gastroesophageal junction.

Methods:

We studied 110 consecutive patients undergoing gastrectomy with IOC margin assessment.

Results:

Gastric margins at IOC utilized the most blocks but were least often positive. In 64% of patients, the entire gastric margin was examined using average six blocks; representative sections were examined in 25% of patients using two blocks. There was no difference in patient outcome between those who had entire vs representative sections of margin examined. Gross variables showing strongest associations with positive margins were tumor size and tumor distance to margin. Tumors sized greater than 2.3 cm had significantly increased risk of positive margin, and tumor distance greater than 4.5 cm to margin was associated with negative margins.

Conclusions:

We conclude representative sections of the closest gastric margin are sufficient to ensure R0 resection in the majority of cases.

PMID:
30020407
DOI:
10.1093/ajcp/aqy062
[Indexed for MEDLINE]

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