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Biochem J. 2018 Jul 17;475(13):2191-2208. doi: 10.1042/BCJ20170521.

Plant mitochondrial protein import: the ins and outs.

Author information

1
School of Molecular Sciences and ARC Centre of Excellence in Plant Energy Biology, University of Western Australia, 35 Stirling Highway, Crawley, Perth 6009, Australia.
2
School of Molecular Sciences and ARC Centre of Excellence in Plant Energy Biology, University of Western Australia, 35 Stirling Highway, Crawley, Perth 6009, Australia monika.murcha@uwa.edu.au.

Abstract

The majority of the mitochondrial proteome, required to fulfil its diverse range of functions, is cytosolically synthesised and translocated via specialised machinery. The dedicated translocases, receptors, and associated proteins have been characterised in great detail in yeast over the last several decades, yet many of the mechanisms that regulate these processes in higher eukaryotes are still unknown. In this review, we highlight the current knowledge of mitochondrial protein import in plants. Despite the fact that the mechanisms of mitochondrial protein import have remained conserved across species, many unique features have arisen in plants to encompass the developmental, tissue-specific, and stress-responsive regulation in planta. An understanding of unique features and mechanisms in plants provides us with a unique insight into the regulation of mitochondrial biogenesis in higher eukaryotes.

KEYWORDS:

cellular targeting; mitochondria; protein import

PMID:
30018142
DOI:
10.1042/BCJ20170521
[Indexed for MEDLINE]

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